The SLIM1 transcription factor is required for arsenic resistance in <i>Arabidopsis thaliana</i>

The transcriptional regulators of arsenic-induced gene expression remain largely unknown. Sulfur assimilation is tightly linked with arsenic detoxification. Here, we report that mutant alleles in the SLIM1 transcription factor are substantially more sensitive to than cadmium. Arsenic treatment caused high levels oxidative stress slim1 mutants, and were impaired both thiol accumulation sulfate accumulation. We further found enhanced roots mutants. Transcriptome analyses indicate an important role for tolerance mechanisms. present study identifies as essential component expression. Our results suggest severe sensitivity mutants by altered redox status.